药物分析教研室现有教师7人，其中博士6人，在读博士1人。教授1人，副教授1人.讲师5人。分别毕业于吉林大学、沈阳药科大学、长春中医药大学、南京药科大学等，学源结构合理。讲授药物分析、药学综合实验、药事管理学、合理用药共4门课程，开设选修课色谱质谱联用技术、体内药物分析、滥用药物分析与应用、中药药物分析、中医学基础。朱鹤云获吉林省第七批拔尖创新人才第三层次人选（2019.11）、吉林省D类人才（2020.7），延边大学及吉林农业大学兼职硕士研究生导师等称号。教研室具有学术兼职如下：中国仪器仪表学会药物质量分析与过程控制分会理事、吉林省检测技术学会理事、吉林省药学会保健食品专业委员会委员、吉林省药学会药物分析专业委员会委员等。曾获吉林省科技进步三等奖一项，吉林省教学成果三等奖一项。发表SCI论文23篇，在研国家自然科学基金一项，吉林省科技厅课题2项、吉林省中药管理局课题1项、卫生厅课题各1项、吉林市科技局课题1项。研究方向有天然药物质量控制、体内药物分析、中药新剂型靶向治疗作用研究、中药药代动力学与代谢组学。

课题：

1. 国家自然科学基金青年基金课题，基于SWATH-MS和质谱成像技术的栀子厚朴汤治疗抑郁症的药效物质基础研究。

2.吉林省科技厅，基于体内效应成分和代谢组学的甘遂半夏汤药效物质基础与作用机制研究

3.吉林省科技厅课题，基于连续可变窗口采集和质谱成像技术的栀子厚朴汤LC-HR-MS/MS分析方法研究与应用。

4.吉林省中医药管理局，黄芩汤治疗溃疡性结肠炎的药效物质基础与质量控制方法研究

5.卫生厅课题，基于RAW264.7细胞小米草抗炎药效物质基础研究

6.吉林市科技局，基于药代动力学的甘草泻心汤防治伊立替康导致迟发型腹泻的机制研究。

论文代表如下：

1.         Heyun Zhu，Jiao Guan，Hui Zhang，Sheng Chang，LimingWang，Jianyi Shi，Bo Feng^∗，Jingkai Gu^∗. Simultaneous determination of ferulic acid, paeoniflorin, and albiflorin in rat plasma by ultra-high performance liquid chromatography with tandem mass spectrometry: Application to a pharmacokinetic study of Danggui-Shaoyao-San. Journal of Separation Science., 2020, 43: 2053-2060. (IF: 3.645)
2. Heyun Zhu, Jiao Guan, Jianyi Shi, Xu Pan, Sheng Chang, Tianyi Zhang, Bo Feng^∗, Jingkai Gu^∗. Simultaneous determination of eight bioactive constituents of Zhi-Zi-Hou-Po decoction in rat plasma by ultra high performance liquid chromatography with tandem mass spectrometry and its application to a pharmacokinetic study. Journal of Separation Science, 2020, 43: 406-417. (IF: 3.645)
3. Heyun Zhu, Kaishun Bi, Fei Han, Jiao Guan, Xiaoshu Zhang, Xinjuan Mao, Longshan Zhao, Qing Li, Xiaohong Hou, Ran Yin^∗. Identification of the absorbed components and metabolites ofZhi-Zi-Da-Huang decoction in rat plasma by ultra-high performanceliquid chromatography coupled with quadrupole-time-of-flight massspectrometry. Journal of Pharmaceutical and Biomedical Analysis, 2015, 111:277-287. (IF: 3.935)
4. Heyun Zhu, Kaishun Bi, Fei Han, Jiao Guana, Zheng Tang, Kelin Chen,Longshan Zhao, Qing Li, Ran Yin^∗, Xiaohong Hou^∗. Simultaneous determination of two iridoid glycosides, twoanthraquinones and four flavonoid glycosides of Zhi-Zi-Da-Huang decoction in rat plasma by UFLC-MS/MS: Application to a comparative pharmacokinetic study in normal and cholestatic liver injury rats. Journal of Chromatography B, 2014, 960: 116–125. (IF: 3.205)
5. Heyun Zhu, Ran Yin^∗, Fei Han, Jiao Guan, Xiaoshu Zhang, Xinjuan Mao, Longshan Zhao, Qing Li, Xiaohong Hou, Kaishun Bi^∗. Characterization of chemical constituents in Zhi–Zi–Da–Huang decoction by ultra high performance liquid chromatography coupled with quadrupole time-of-flight mass spectrometry. Journal of Separation Science, 2014, 37: 3489-3496. (IF: 3.645)
6. Heyun Zhu, Xiurong Zhang^∗, Jiao Guan, Baiji Cui, Longshan Zhao, Xu Zhao. Pharmacokinetics and tissue distribution study of schisandrin B in rats by ultra-fast liquid chromatography with tandem mass spectrometry. Journal of Pharmaceutical and Biomedical Analysis, 2013, 78– 79: 136– 140. (IF: 3.935)
7. Jiao Guan¹, Liming Wang¹, Jia Jin, Sheng Chang, Xiao Xiao, Bo Feng^∗, Heyun Zhu^∗. Simultaneous determination of calycosin-7-O-β -D-glucoside,cinnamic acid, paeoniflorin and albiflorin in rat plasma byUHPLC-MS/MS and its application to a pharmacokinetic study ofHuangqi Guizhi Wuwu Decoction. Journal of Pharmaceutical and Biomedical Analysis, 2019, 170: 1–7. (IF: 3.935)
8. Jiao Guan, Xiurong Zhang^∗, Bo Feng, Donghai Zhao, Tong Zhao, Sheng Chang, Liming Wang, Heyun Zhu^∗. Simultaneous determination of ferulic acid and gastrodin of Tianshu Capsule in rat plasma by ultra-fast liquid chromatography with tandem mass spectrometry and its application to a comparative pharmacokinetic study in normal and migraine rats. Journal of Separation Sciemce, 2017, 40: 4120-4127. (IF: 3.645 )
9. Yuxuan Li ^#, Yue Cui^#, Lele Li, Xiaoyin Lin, Xinxin Zhou, Heyun Zhu^∗, Bo Feng^∗. Ultra-high-performance liquid chromatography coupled with quadrupole time of flight mass spectrometry method for quantifying polymer poloxamer 124 and its application to pharmacokinetic study.  Journal of Separation Sciemce, 2021, 44: 3822-3829. (IF: 3.645)
10. Yuxuan Li^†, Yue Cui^†, Lele Li, Xiaoyin Lin, Xinxin Zhou, Heyun Zhu^∗, Bo Feng^∗. A UHPLC-Q-TOF/MS method for the determination of poloxamer 124 and its application in a tissue distribution study in rats. Analytical Methods, 2021, 13:5516-5522. (IF: 2.896 ) .

11.Yue Cui, Huanhuan Yang, Jixue Jing， et al. Rapid characterization of chemical constituents of Gansuibanxia decoction by UHPLC-FT-ICR-MS analysis, Journal of Pharmaceutical and Biomedical Analysis, 2020, 179: 113029.

12. Ma yinghui.Study on intestinal transport of Veratrum alkaloids compatible with Panax ginseng across the Caco-2 cell monolayer model by UPLC-ESI-MS method,Chinese Chemical Letters,2016,27:215-220.IF=6.779
13. Ma yinghui. Studies on Intestinal Transport of Ginsenoside Compatibility with Veratrum nigrum via Caco-2 Cell Monolayer Model Coupled with UPLC-ESI-MS Method, Chemical Research in Chinese Universities，2015,31(6):914-918.IF=1.307