教育经历

承担项目情况

1.基于连续可变窗口采集技术的泊洛沙姆聚合物LC-HR-MS/MS 分析方法研究与应用，国家自然科学基金面上项目，2018年，排名第1
2.泊洛沙姆聚合物LC-HR-MS/MS分析方法建立及其药代动力学研究，吉林省科技厅，2018年，排名第1
3.基于谱效关系的关龙胆抗肝损伤物质基础及质量评价研究，吉林省中医药管理局，2017年，排名第1
4.院内制剂乌白祛痨颗粒的研发，吉林省中医药管理局，2015年，排名第1
5.基于活性导向的标准组分模式研究关龙胆保肝作用物质基础研究，吉林省卫生厅,2013年，排名第1
6.夏枯草诱导SKOV-3细胞凋亡的活性成分及分子机制研究，吉林省教育厅，2012年，排名第1
7.龙胆抗肝损伤活性组分的药物代谢动力学研究，吉林省科技厅，2009年，排名第1
8.夏枯草抗肿瘤有效部位的化学成分和活性研究，吉林省教育厅，2008，排名第1
9.基于药学专业集群转型背景下应用型人才培养模式的探索与实践,吉林省教育厅，2016，排名第1
10.基于PDCA模式的药学类专业产教融合人才培养体系优化研究，吉林省教育厅，2019年，排名第1   

代表性著作     

1. 东北道地药材龙胆和五味子保肝作用的物质基础及其制剂研究，吉林省科学技术奖三等奖，2018，排名第1
2. 药用新辅料乙基化β-环糊精及其药物包合物的研究，吉林省科技进步三等奖，2008年，排名第1
3. 新型纳微递药系统提高药物递送的靶向性及功效的研究，吉林省科学技术奖二等奖，2021年，排名第2
4. Bo Feng, Heyun Zhu, Jiao Guan, Longshan Zhao, Jingkai Gu, Lei Yin, J. Paul Fawcettd, Wenshu Liu*. A rapid and sensitive UFLC-MS/MS method for the simultaneous determination of gentiopicroside and swertiamarin in rat plasma and its application in pharmacokinetics. Journal of  Pharmacy and  Pharmacology. 2014,66: 1369-1376. ( IF: 3.765) .
5. Yuxuan Li #, Yue Cui#, Lele Li, Xiaoyin Lin, Xinxin Zhou, Heyun Zhu∗, Bo Feng∗. Ultra-high-performance liquid chromatography coupled with quadrupole time of flight mass spectrometry method for quantifying polymer poloxamer 124 and its application to pharmacokinetic study.  Journal of Separation Science, 2021, 44: 3822-3829. (IF: 3.645)
6. Yuxuan Li†, Yue Cui†, Lele Li, Xiaoyin Lin, Xinxin Zhou, Heyun Zhu∗, Bo Feng∗. A UHPLC-Q-TOF/MS method for the determination of poloxamer 124 and its application in a tissue distribution study in rats. Analytical Methods, 2021, 13: 5516-5522. (IF: 2.896)
7. Yixuan Feng, Lele Li, Yuxuan Li, Xinxin Zhou, Xiaoying Lin, Yue Cui, Heyun Zhu*, Bo Feng*.  A MSALL quantitative method for the determination of Poloxamer 188 in rat plasma by UHPLC–Q-TOF/MS and its application to pharmacokinetic study. Biomedical Chromatography, 2021, e5265. (IF: 1.902)
8. Yixuan Feng†, Lele Li †, Yuxuan Li , Xinxin Zhou, Xiaoying Lin, Yue Cui *, Heyun Zhu* , Bo Feng*. Tissue Distribution Study of Poloxamer188 in Rats by Ultra-High-Performance Liquid Chromatography Quadrupole Time of Flight/Mass Spectrometry with MSALL-Based Approach. Molecules 2021, 26, 5644-5654. (IF: 4.411)
9. Lele Li*, YangWang*, Yuxuan Li, Heyun Zhu*, Bo Feng*. A pseudotargetedmethod based on sequential window acquisition of all theoretical spectra mass spectrometry acquisition and its application in quality assessment of traditional Chinesemedicine preparation-Yuanhu Zhitong tablet. Journal of Separation Science, 2021: 1-9. (IF: 3.645)
10. Jiao Guan1, Liming Wang1, Jia Jin, Sheng Chang, Xiao Xiao, Bo Feng∗, Heyun Zhu∗. Simultaneous determination of calycosin-7-O-β -D-glucoside,cinnamic acid, paeoniflorin and albiflorin in rat plasma byUHPLC-MS/MS and its application to a pharmacokinetic study ofHuangqi Guizhi Wuwu Decoction. Journal of Pharmaceutical and Biomedical Analysis, 2019, 170: 1–7. (IF: 3.935)